Electrospinning of liquefied banana stem residue in conjugation with hydroxyapatite nanocrystals: towards new scaffolds for bone tissue engineering

Electrospun fibers have high structural similarity to the extracellular matrix. Some researchers tried fabricate cellulose nanofibers using electrospinning, although fabricated usually exhibited a non-uniform texture. Moreover, mats always suffer from low biological and mechanical properties. Thus, objective of this study was first produce naturally occurring banana pseudo-stem. The native then used electrospin in order determine how Taguchi L9 orthogonal array can be defect-free fibrous mat. Finally, incorporated with hydroxyapatite (HA) nanoparticles generate new construct which provides suitable environment for cell attachment HA act as strong filler increasing results revealed that concentration solution applied voltage had greatest effect on morphology fibers. morphological characterization nanocomposites showed they uniform nanofibrous texture without any significant bead, splashing or particle agglomeration. According tests, samples containing higher significantly strength. obtained bioactivity analysis indicated an interesting transformation into flake-like structure confirmed scaffolds. vitro studies pronounced increase proliferation bone cells cellulose/HA compared neat cellulose. Given strength activity, scaffold promising regeneration applications.